Biomedical Optics Instrumentation Group (GIOB)

GIOB

Students

Grecia Beatriz Magdaleno Martínez

Grecia Beatriz Magdaleno Martínez

  • 2nd year of Master’s in Biomedical Sciences and Technologies
  • Education:
    • Bachelor's in Biomedical Engineering
  • Research Interests: CT Imaging Spectrometry, Machine Learning, Deep Learning, Biomedical Image and Signal Processing
  • Thesis: Application of CT Imaging Spectrometry and Deep Learning in the Identification of Biological Pig Tissues
  • Project Summary: This project focuses on classifying images of various biological pig tissues obtained from the CT Imaging Spectrometry (CTIS) system using deep and convolutional neural networks. The goal is to lay the groundwork for identifying lesions in human skin. The CTIS system is an instantaneous acquisition technique that captures a data cube with detailed spatial and spectral information. It offers a new non-invasive alternative for hyperspectral data acquisition applicable to various biological and biomedical fields.
  • Hobbies: Reading, science communication, animation, traveling.
Odalys Fabiola Aguilar Mejía

Odalys Fabiola Aguilar Mejía

  • 2nd year of Master’s in Biomedical Sciences and Technologies
  • Education:
    • Bachelor's in Biotechnology Engineering
  • Research Interests: My personal research interest focuses on exploring and expanding the applications of Raman spectroscopy within molecular biology. I am particularly motivated by the potential of this technique to identify genes associated with various diseases, which could revolutionize current diagnostic and treatment methods in medicine. My goal is to develop innovative methods that harness the precision of Raman spectroscopy to advance personalized medicine and improve healthcare.
  • Thesis Project: Replacing PCR Electrophoresis with Raman Spectroscopy for the Identification of Candida albicans
  • Project Summary: The aim of this study is to conduct Polymerase Chain Reaction (PCR) to amplify the HWP1 gene of the yeast Candida albicans. The gene will then be identified and verified using Raman spectroscopy. This method is proposed as a precise, rapid, and efficient alternative, and its results will be compared with those obtained through electrophoresis to validate its effectiveness in genetic identification.
  • Hobbies: Reading about scientific innovations in the biological field, teaching science, walking, and hiking.
Héctor David Barrón Flores

Héctor David Barrón Flores

  • 2nd year of Master’s in Biomedical Sciences and Technologies
  • Education:
    • Biomedical Engineer
  • Research Interests: I am interested in the potential applications of Raman spectroscopy in the analysis of biological tissues and how artificial intelligence can enhance the accuracy of medical diagnostics. I aim to explore how these technologies, when combined, can offer non-invasive and more precise solutions for disease detection, contributing to the advancement of medicine and healthcare.
  • Thesis Project: Raman Mapping Spectroscopy for the Detection of Skin Diseases In Vitro Using AI-based Image Processing.
  • Project Summary: The project focuses on developing a non-invasive method to identify and differentiate skin diseases by integrating Raman spectroscopy and artificial intelligence techniques in a pixel-by-pixel scanning system. This involves designing, manufacturing, and implementing an XYZ instrument for three-axis movements and 200-micron scans, integrating a Raman spectrometer to capture spectral signatures from synthetic skin tissue. Skin and skin diseases will be reproduced in synthetic tissue to acquire spectral data. The data will be stored and processed using deep learning to identify a biomarker.
  • Hobbies: Weightlifting, boxing, hiking, chess.
Nallely Arroyo Silva

Nallely Arroyo Silvaa

  • 1st year of Ph.D. in Biomedical Sciences and Technologies
  • Education:
    • B.Sc. in Mechatronics
  • Research Interests: Raman Spectroscopy, Biosignal Processing, Artificial Intelligence, and Machine Learning
  • Thesis Project: Evaluation of the capacity of Raman spectroscopy for the identification of N-acetylneuraminic acid in saliva for breast cancer diagnosis.
  • Project Description: The purpose of the project is to assess the capacity of Raman spectroscopy, without added nanoparticles, for identifying N-acetylneuraminic acid in saliva as a non-invasive tool for breast cancer diagnosis. The initial stage involves an optical characterization of the biomarker, followed by biomarker identification within synthetic saliva, requiring spectral data processing using machine learning techniques.
  • Hobbies: Reading, listening to music, watching series, swimming, creating crafts with mache paper, hand embroidery.
Israel Rojas Rosas

Israel Rojas Rosas

  • 1st year of Ph.D. in Biomedical Sciences and Technologies
  • Education:
    • B.Sc. in Mechatronics
  • Research Interests: Raman Spectroscopy, Chronic Degenerative Diseases
  • Thesis Project: Characterization and detection of Trimethylamine N-oxide (TMAO) in the urine of patients with cardiovascular diseases.
  • Project Description: Current research focuses on characterizing and detecting Trimethylamine N-oxide (TMAO) in the urine of individuals with cardiovascular diseases or at risk. Raman spectroscopy is used to analyze TMAO at various concentrations. Synthesized urine samples will be used for validation, extending the application of the method to patients with cardiovascular diseases and a healthy control group.
  • Hobbies: Reading, swimming, painting, and engaging in scientific outreach.
Martin de Jesús Torres Vargas

Martin de Jesús Torres Vargas

  • 4th year of the Ph.D. in Optics
  • Education:
    • Master's in Optics
    • B.Sc. in Mechatronics
  • Research Interests: Diffuse Reflectance Spectroscopy, Monte Carlo Simulation, Cancer
  • Thesis Project: Development of a device for breast cancer detection using diffuse reflectance spectroscopy.
  • Project Description: The project involves creating a device for breast cancer detection using diffuse reflectance spectroscopy. It is currently in the safety phase, utilizing Monte Carlo simulations to ensure the device does not cause harm to patients. Anthropometric studies and mathematical analysis of radiative transport are also conducted to validate the model.
  • Hobbies: Video games, series, movies, and singing.
Héctor Nahum Chavarría Lizárraga

Héctor Nahum Chavarría Lizárraga

  • 4th year of the Ph.D. in Optics
  • Education:
    • Master in Optics
    • Mechatronics Engineer
  • Research interests: Biophotonics, Raman Spectroscopy, Machine Learning, computational quantum chemistry, Electronic design, Humanoid and industrial robotics and automatic control.
  • Thesis project: Raman spectroscopy applying the SORS technique to the study of bone tissues and optomechanical mapping.
  • Description of your thesis project: my project is based on the diagnosis of osteoporosis and osteoarthritis, applying the optomechanical mapping technique with SORS in silico, in vitro and invivo of biological tissues. Everything is based on the determination of the levels of bone mineralization and its detection through the skin. The mineral molecules of the bone, such as carbonate and calcium phosphate, will be simulated to obtain the vibrational modes and frequencies to later compare with the experimental, in addition, synthetic simulators will be developed for tissue penetration depth tests. The Raman spectra obtained will be analyzed and classified using machine learning techniques to generate an efficient diagnosis.
  • Hobbies: Writing poetry and literature, listening to music and playing piano, popular science and cooking
Noe Vazquez Osorio

Noe Vazquez Osorio

  • 3rd year of Ph.D. in Optics
  • Education:
    • Master's in Optics
    • B.Sc. in Mechatronics
  • Research Interests: Optical Design, Optical Instrumentation, Signal Pre-processing, Additive Manufacturing
  • Thesis Project: Design and construction of a Raman spectrometer for early detection of degenerative diseases.
  • Project Description: The objective is to design and build a Raman spectrometer with sufficient resolution to measure biomarkers in the human body and contribute to the early detection of diseases such as diabetes. Czerny-Turner configuration and aspheric methods to correct aberrations will be employed. Additive manufacturing with optical response analysis is proposed.
  • Hobbies: Reading, swimming, playing soccer, woodworking, painting, walking, movies, and playing ping pong.
José Eduardo Leon Leyva

José Eduardo Leon Leyva

  • 3rd year of Ph.D. in Optics
  • Education:
    • Master's in Optics
    • B.Sc. in Physics
  • Research Interests: Optical techniques applied to biomedicine, Light Dosimetry
  • Thesis Project: Analysis of the propagation of a monochromatic plane wave in an optically active medium to improve light dosimetry in breast cancer therapies.
  • Project Description: Currently developing a doctoral thesis in the specialty of optics, focusing on analyzing light propagation in synthetic tissues to improve light dosimetry in light therapies for breast cancer.
  • Hobbies: Hiking, athletics, listening to music, soccer.
Rebeca María Bruzual Roa

Rebeca María Bruzual Roa

  • 2nd year of Ph.D. in Optics
  • Education:
    • Master's in Science in Optics
    • B.Sc. in Physics
  • Research Interests: Raman Spectroscopy, Data Analysis (machine learning, deep learning)
  • Thesis Project: Development of a method for the non-invasive detection of Type 2 Diabetes using Raman spectroscopy in different areas of the skin.
  • Project Description: The project aims to use Raman scattering to non-invasively identify Type 2 Diabetes (T2D). Raman spectral measurements will be taken in different areas of the skin, and a technique will be standardized to measure T2D biomarkers, such as glycosylated hemoglobin and glucose. Spectral data will be acquired from healthy, pre-diabetic, and T2D patients for analysis, with plans to capture data from 900 patients for statistical analysis.
  • Hobbies: Scientific outreach, traveling, swimming.
Leopoldo José Ramírez Landaeta

Leopoldo José Ramírez Landaeta

  • 1st year of Ph.D. in Optics
  • Education:
    • Ph.D. in Human Machine Satellite Environment
    • Master's in Science in Optics
    • B.Sc. in Physics
  • Research Interests: Diffuse Reflectance and Raman Spectroscopy, Optical Design, Data Analysis (machine learning, deep learning)
  • Thesis Project: Quantification of biological components in lettuce using optical techniques.
  • Project Description: This field study project focuses on descriptive and explanatory research of optical techniques for quantifying biological components in lettuce. Techniques such as Diffuse Reflectance, Absorbance, and Raman will be used to quantify chlorophyll a and b concentration and detect sugar in two lettuce varieties grown hydroponically. The study takes place in an unheated, ventilated greenhouse throughout their growth cycles.
  • Hobbies: Scientific outreach, astronomical observation, traveling, reading, meditation, and psychonautics.
Alejandra López Saldaña

Alejandra López Saldaña

  • 2nd year of the Master's Degree in Biomedical Sciences and Technologies
  • Education:
    • Pharmaceutical Chemist Biotechnologist
  • Research interests: Computational quantum chemistry, biomarker simulation.
  • Thesis project: Simulation of Biomarkers associated with chronic degenerative diseases using Raman spectroscopy.
  • Hobbies: Dissemination of science, swimming, dancing, I really like to travel and discover new places, perspectives and people.